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PRODUCTS > SUPRALIMUS Supralimus-Core | Supralimus | Coronnium | Infinnium | Matrix Download Brochure Features of Supralimus®: The outcome of the Supralimus® is based on the three powerful tools. The CE approved The Millennium Matrix® Stent, Sirolimus Drug and fully biodegradable polymers coating. It has drug Sirolimus, which has dual mechanism of action, regulates inflammatory cell function, blocks smooth muscle cell proliferation. The Millennium Matrix® Coronary Stent: • The unique design and strut locking mechanism offers excellent radial strength and minimum recoil even with thinner strut. • Smooth surface, round edges and thin struts of stent minimizes vessel injury and obliging in reduces thrombus formation incidence.   Therapeutic Agent-Sirolimus: • A cytostatic drug that has potent immunosuppressive and antiproliferative properties. • Inhibits expression of key cytokines necessary for the smooth muscle cell proliferation from the G1 to the S phase of the cell cycle. • As a part of a DES system, Sirolimus targets the very cause of ISR, proliferating vascular smooth muscle cells, arresting their proliferation. Surface Morphology of Supralimus®::       • Coating on the stent is uniform & smooth • No crack & deformation • Expanded stents shows elasticity, flexibility & adhesion properties of the biodegradable polymers Drug Carrier-Biodegradable Polymers: • Coating of fully biodegradable polymeric blend used for controlled delivery of drug in to the adjacent tissue. • The polymeric chains are breakdown into monomers and enter into Crab’s cycle and finally converted into CO2 and H2O which are excreted through urine. Preclinical: • No In stent thrombosis • Thin Neointima • No cytotoxic response • Proven In vitro and In vivo hemocompatibility Supralimus® Stent Specifications: Description Supralimus® Stent Available Stent Lengths 11,16, 19, 23, 29, 33, 39 mm Available Stent Diameters 2.25, 2.50, 2.75, 3.00, 3.50. 4.00 mm (4-Crown) Stent Material 316L Stainless Steel (SS) Stent Design Laser cut from seamless tubing in a serpentine pattern Stent Platform The CE approved Millennium Matrix® Stent Stent Strut thickness/ width 0.08mm (80µ) / 0.11mm (110µ) Average Stent Foreshortening < 1% Average Recoil < 5% Average Radial Strength Resists at least 1 bar Metal to Artery Ratio (φ 3.0mm) 13.1% Drug Sirolimus Polymers Type Biodegradable Polymers Supralimus-Core | Supralimus | Coronnium | Infinnium | Matrix

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